Searchable abstracts of presentations at key conferences in endocrinology

ea0010p35 | Diabetes, metabolism and cardiovascular | SFE2005

Programming of insulin sensitivity in lean and obese sheep

Gardner D , Tsintzas K , Smonds M

BackgroundInsulin resistance is associated with obesity, metabolic syndrome and hypertension. These risk factors for type 2 diabetes and cardiovascular may be programmed by the early diet. Here we assessed insulin sensitivity in pre- and postnatally nutritionally challenged offspring at 1 yr of age in sheep.Methods37 twin-bearing ewes were randomly allocated to receive either a control (C, n=24) or nutrient r...